Another study demonstrated that EVs can be collected from the sera of patients with acute myeloid leukemia (AML), which contains higher levels of membrane associated TGFβ-1 and FasL than control sera [77] and that the treatment of Natural Killer cells with AML patients’exosomes results in TGFβ-1-mediated cytotoxicity of the target cells. The gene discussed is FASLG; the disease is acute myeloid leukemia.