Prevalence of NAFLD was 59.2% in the cohort of psoriatic patients. In these patients NAFLD was significantly associated with metabolic syndrome and psoriatic arthritis. Compared with the non-psoriatic NAFLD cohort, psoriatic patients with NAFLD were likely to have more severe NAFLD reflected by either non-invasive NAFLD Fibrosis score or AST/ALT ratio >1. This evidence concerns the gene GPT and fibrosis.