Prevalence of psoriasis was 5.1% (by a validated algorithm). Prevalence of NAFLD was higher in psoriatic patients than in participants without psoriasis (46.2% vs. 33.3%, p = 0.005). Psoriasis was associated with NAFLD (OR 1.70, 95% CI 1.1–2.6, p = 0.01), independent of age, sex, alcohol consumption, pack-years and smoking status, metabolic syndrome, and serum ALT levels. The gene discussed is GPT; the disease is psoriasis.