The identification of mutex patterns concerning other proteins belonging to the Ras family suggests that beyond KRAS, HRAS and NRAS other minor genes, such as RRAS2, could play a “Ras-like” role in promoting pro-proliferative activity via the activation of the Raf-ERK pathway of MAP kinases [32] in uterine and cervical cancers (Additional file 1: Figure S2). Here, RAF1 is linked to cervical cancer.