GNAS and pseudohypoparathyroidism type 1A: The maternal inheritance of Gsα mutations cause AHO with multihormone resistance [termed pseudohypoparathyroidism type IA (PHPIA)], and the paternal inheritance of Gsα mutations only lead to AHO phenotype [termed pseudopseudohypoparathyroidism (PPHP)] [11,17].