IL6 and gastric cancer: Prominent among these are models designed to mimic alterations in pro-inflammatory cytokines and signaling pathways that are deregulated in human gastric cancer, including IL-1β; IFNγ; Wnt/β-catenin; Cox2 and prostaglandin E2; Smad4; and gp130, which transduces signals from the pro-inflammatory cytokines IL-6 and IL-11 (reviewed in [7]).