PMAIP1 and medulloblastoma: In addition, gene expression datasets from medulloblastoma tumors (Kool et al., 2008, Northcott et al., 2012, Robinson et al., 2012), a pediatric cancer in which MYCN is often amplified (Ryan et al., 2012), indicated that PMAIP1 mRNA expression positively correlated with MYCN mRNA expression (Figures 1F, S1E, and S1F).