In addition, gene expression datasets from medulloblastoma tumors (Kool et al., 2008, Northcott et al., 2012, Robinson et al., 2012), a pediatric cancer in which MYCN is often amplified (Ryan et al., 2012), indicated that PMAIP1 mRNA expression positively correlated with MYCN mRNA expression (Figures 1F, S1E, and S1F). Here, MYCN is linked to cancer.