This gene shows differential expression between primary and secondary glioblastoma, while PTEN loss, EGFR amplification, and loss of heterozygosity (LOH) of chromosome 10 are associated with primary glioblastoma, and ATRX mutation, loss of p53, and LOH of chromosome 19 are common in secondary glioblastoma. This evidence concerns the gene ATRX and glioblastoma.