Oncogenic role of miR-107 in regulating tumor invasion and metastasis in gastric cancer by targeting DICER1 (Li et al., 2011) and in colorectal cancer by targeting metastasis suppressors death-associated protein kinase (DAPK) and Krüppel-like factor 4 (KLF4; Chen et al., 2012) has been proposed. The gene discussed is KLF4; the disease is colorectal cancer.