However, mutations in TAR DNA-binding protein 43 (TDP-43, TARDBP), fused in sarcoma/translocated in liposarcoma (FUS/TLS), vesicle-associated membrane protein-associated protein B (VAPB) and other genes have been reported (Andersen and Al-Chalabi, 2011). The gene discussed is TARDBP; the disease is sarcoma.