MKI67 and breast carcinoma: In another study, Ekmekcioglu et al. [39] also investigated the prognostic value of FDG-PET uptake in breast carcinomas by comparing it with histopathological and immunohistochemical prognostic factors (tumor size, histological type, histological grade, pleomorphism, mitosis count, lymphatic invasion, necrosis, estrogen negativity, Ki-67 level, axillary lymph node involvement, and triple negativity).