A molecular signature composed of 13 splice variant biomarkers, including C5ORF4, COPZ1, MACF1, WLS, PRG3, ZNF160, EFTUD2, MAP4K1, MPP1, PKM2, SLC14A1-s, SLC14A1-l and ZNF134, distinguished PD patients from APD and healthy controls with 90% sensitivity and 94% specificity [27]. The gene discussed is EFTUD2; the disease is Parkinson disease.