HNF4A and liver cancer: Reintroducting HNF4α corrected the dysregulated cell cycle induced by knocking down endogenous HNF4α; similarly, reintroducing Exo70 also reversed the cell cycle progression changed by knocking down Exo70 (Figure 5A–5B), thus confirming the critical roles of HNF4α and Exo70 in the regulation of cell cycle in hepatic cancer cells.