Immunohistochemical staining of a cohort of 468 sarcomas by Schildhaus et al., reported pronounced LSD1 expression specifically in highly malignant tumor groups including synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors and malignant peripheral nerve sheath tumors (MPNST) [70]. The gene discussed is KDM1A; the disease is rhabdomyosarcoma.