The two single hubs in communities B and L (Table 4) are paternally imprinted genes: IGF2AS, in community B, encodes a long non-coding RNA (lncRNA), the antisense transcript of the insulin-growth factor 2 gene [234], and IPW, in community L, codes a lncRNA widely expressed in adult and fetal tissues and associated to Prader-Willi syndrome [235, 236]. This evidence concerns the gene IGF2-AS and Prader-Willi syndrome.