Moreover, the methylation status of nine CpG sites in the CALB2 promoter of epithelioid (n = 57) and biphasic (n = 23) mesothelioma samples from The Cancer Genome Atlas (TCGA) database generally showed low methylation levels, particularly at CpG sites nearest to the TSS (Figure 2C). The gene discussed is CALB2; the disease is mesothelioma.