Specific examples include the use of EGFR tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC) with an EGFR mutation [8], BRAF inhibitors in melanoma harboring BRAF mutations [9,10], or imatinib for chronic myelogenous leukemia [11,12]. Here, EGFR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.