Compared with the pooled normal brain tissue, GBP1 expression was significantly elevated in 15 of 25 (75%) GBM samples, and importantly, displayed a positive correlation with EGFRvIII status (p < 0.05, Kruskal Wallis test, Figure 2A and 2B), suggesting that EGFRvIII signaling induces GBP1 expression in GBM. Here, GBP1 is linked to glioblastoma.