Resistance to irradiation of SCLC cells has previously been identified with N-acetylglucoaminyltransferase V (Gnt-V) over-expression and upregulation of Gnt-V in vivo causing an increase in N-cadherin, vimentin and ZEB2, again suggesting a link between radiosensitivity and EMT-like change [25]. Here, ZEB2 is linked to small cell lung carcinoma.