As shown in Figure 3A, Jurkat cells infected with HIV-1 and incubated with pH1N1 for another three days, had higher levels of HIV-1 RNA relative to cell with HIV-1 infection alone, suggesting that pH1N1 infection increases HIV-1 replication in co-infected cells in Jurkat cells and in CD4+ T cells (Figure S3C). The gene discussed is CD4; the disease is HIV-1 infection.