MAPT and Alzheimer disease: Further, downregulation of miR-15, miR-16, miR-132 and miR-497 is also associated with the accumulation of phospho-tau, whereas miR-106a, miR-106b, miR-107, miR-124, miR-137, miR-153, miR-195 and miR-520c are linked to deposition of Aβ-plaques in AD [75,76,77].