Based on the cellular distribution of tau pathology, disorders with neuronal (Pick disease, PiD; AD, neurofibrillary tangle (NFT)-dementia or primary age-related tauopathy, PART), mixed neuronal and glial (progressive supranuclear palsy, PSP; corticobasal degeneration, CBD; argyrophilic grain disease, AGD) and glia-predominant forms (globular glial tauopathies, GGT) can be distinguished. The gene discussed is MAPT; the disease is argyrophilic grain disease.