FUS and synucleinopathy: Based on the major protein showing depositions in the central nervous system, neurodegenerative proteinopathies are classified as tauopathies, α-synucleinopathies, TDP-43 proteinopathies, FUS/FET proteinopathies, prion diseases, trinucleotide repeat diseases, neuroserpinopathy, ferritinopathy, and cerebral amyloidoses (Table 1).