However, the conditioned medium from GATA1- or SET7-overexpreesing breast cancer cells with VEGFR2 knockdown had similar effect on angiogenesis to the conditioned medium from GATA1- or SET7-overexpreesing breast cancer cells (Supplementary Figure S10E), suggesting that VEGFR2 is not required for GATA1 or SET7 modulation of VEGF expression in breast cancer cells. This evidence concerns the gene SETD7 and breast carcinoma.