CD4 and colitis: In this context it is important to note, that theadoptive/intravenous transfer of MDSCs in experimental models of colitis (DSS, TNBS,IL-10−/−,CD4+CD25− T cell transfer intoRag1−/− mice) is associated withamelioration of intestinal inflammation11, 13, 14, 15, 16, 17, 38, 39, 41, whereas anti-Gr-1 antibodytreatment worsened DSS-induced colitis38.