NFKB1 and colitis: To investigate whether inhibition of colitis in gp130757F/F miceis due to altered gp130 signalling, we examined activation of signallingmolecules STAT1, STAT3, ERK1/2 and NfκB in the colon of DSS-treatedand untreated gp130757F/F and WT mice (Fig.4).