TP53 and B-cell chronic lymphocytic leukemia: Before treatment we found mutations in genes that are recurrently mutated in CLL, (ATM, BIRC3, CHD2, DDX3X, IRF4, ITPKB, KLHL6, MYD88, NOTCH1, NFKBIE, SF3B1, SPEN, TP53 and ZMYM3) in nine patients (69%) with a mean of one mutation per case (min–max: 0–4).