SOX2 and non-small cell lung carcinoma: The negative correlation between SOX2 and ZEB1 was indicated by the bioinformatical analysis using the 105 NSCLC cell lines dataset but not the 178 lung SCC specimens dataset (Figs 1 and 2); however the biological analysis indicated that SOX2 intrinsically regulates ZEB1 in lung SCC cells, suggesting the requirement of validating bioinformatical analysis by biological experiments.