This research addresses two above-mentioned predictions of central and peripheral physiological mechanisms associated with HbA1c and FPG and thus different central and peripheral pathophysiological forms of type 2 diabetes by studying the relationships between polymorphisms of central (DRD2), hemodynamic (ACE), and metabolic (PGC1A) genes and these two glycemic indicators in diabetic patients and nondiabetic control group. The gene discussed is PPARGC1A; the disease is type 2 diabetes mellitus.