IL17A and diabetes mellitus: Interestingly, inhibition of Th17 cell differentiation using recombinant IL-25 (IL-17E, a member of IL-17 family cytokine with an anti-inflammatory property and promoting Th2 cell differentiation) had more profound effect than that blocking a single Th17 cytokine, IL-17 using anti-IL-17 antibody in prevention of diabetes.