Our results showed that the C/T genotype was enriched in the MPN group compared to healthy controls (P = 0.01; Odd Ratio (OR) = 2.361; 95% Confidence Interval (CI) = 1.206–4.624), suggesting that TET2 rs3733609 C/T genotype was associated with a predisposition to sporadic MPNs. The gene discussed is TET2; the disease is myeloproliferative neoplasm.