We analyzed BMMNCs samples from MPN patients with or without rs3733609 C/T genotype using a real-time quantitative-PCR assay, which showed that the expression of TET2 mRNA in rs3733609 C/T genotype decreased by 71.2% than that in T/T genotypes (P = 0.006). This evidence concerns the gene TET2 and myeloproliferative disorder.