Patients with RA who relapsed were not different from patients with RA who did not relapse with regard to anti-CCP (p = 0.89), IgA-RF (p = 0.86) or IgM-RF (p = 0.86) positivity; smoking habit (p = 0.34); or biologic type (53.8 % adalimumab-treated patients vs. 46.2 % etanercept-treated patients had disease relapse; p = 0.79). The gene discussed is CD79A; the disease is rheumatoid arthritis.