In Table 4, our results showed that Twist2 and E-cadherin expression had an obviously negative correlation in pancreatic cancer tissues (r = − 0.417, P < 0.05), however, it had no obvious correlation between Twist1 and E-cadherin (r = − 0.114, P > 0.05). The gene discussed is CDH1; the disease is familial pancreatic carcinoma.