Thus, we examined gene sets described by Zheng et al.24, which compared 185 laser captured human dopaminergic neuron samples and discovered 10 gene sets with previously unknown associations with PD, including genes that are responsive to peroxisome proliferator–activated receptor γ coactivator-1α (PGC-1α) (which are higher in control than PD). This evidence concerns the gene PPARGC1A and Parkinson disease.