The expression of the Th-17-inducing cytokines IL-1beta, IL-6 and IL-23 was significantly increased in ocular BD patients as compared with normal controls (p < 0.01, p < 0.01, p < 0.01), and BTLA stimulation decreased their production by DCs in both patients (p < 0.05, p < 0.05, p < 0.05) and controls (p < 0.05, p < 0.05, p < 0.05)(Fig. 5C–E). This evidence concerns the gene IL1B and Behcet disease.