Five pathways wereenriched for genes in the module d-1 (MAPK1, MITF,RAF1, JAK1, and STAT3):pancreatic cancer (P=5.47E-04), melanoma (P=8.52E-03), melanogenesis (P=1.48E-02),acute myeloid leukemia (P=7.67E-03), and cancer pathways (P=3.69E-03). The gene discussed is MAPK1; the disease is familial pancreatic carcinoma.