It was also shown that mitochondrialrespiration is substantially enhanced in NSCLC cells (28), while inhibition of mitochondrial electron transport prevents the growthof human lung cancer A549 cells (29).NDUFS1 is already considered to be a prognostic marker for NSCLC(30), so we predict that the DEGsNDUFA2, NDUFB8, NDUFA7,NDUFA1, NDUFB1, NDUFS7,NDUFV1, NDUFV2, and NDUFS3 play animportant role in lung adenocarcinoma carcinogenesis, and may become diagnostic markersfor lung cancer. This evidence concerns the gene NDUFS3 and lung adenocarcinoma.