We also confirmed the interaction between SETDB1 and ΔNp63α at endogenous level in MCF- 7 breast cancer cell line, which express exclusively the ΔNp63α isoform (Figure 1B lane 3; Supplementary Figure S1A–S1D), and in normal human epidermal keratinocytes (Supplementary Figure S2). This evidence concerns the gene SETDB1 and breast cancer.