Activation of the Wnt-planar cell polarity signaling pathway in breast cancer cells as a result of treatment with fibroblast-secreted exosomes as well as secretion of HSP90α shown to be promoted by breast cancer exosomes or EDIL-3 via bladder cancer exosomes are just few examples of how exosomes can influence cell migration and invasion in cancer models [77–79]. The gene discussed is HSP90AA1; the disease is cancer.