EGFR and malignant colon neoplasm: Examples are receptor tyrosine kinases, e.g., ErbB, derived from the epidermal growth factor receptor [48], which is overexpressed in many cancers especially breast cancer and is targeted by the drug Herceptin, and src-like non-receptor tyrosine kinases, e.g., src, which is mutated in many cases of cancer of the colon, liver, lung, breast and the pancreas [49].