Deletions at locus 9p21.3 (including the CDKN2A/B locus) were found in 4/4 of the MPNST cell lines, in accordance with previous data showing that > 80% of MPNSTs presented somatic alterations of CDKN2A/B [12]. The gene discussed is CDKN2A; the disease is malignant peripheral nerve sheath tumor.