CRABP2 and neoplasm: However, the downregulation of CRABP2 in T tissues was closely correlated with the position of tumor (**p = 0.001 for middle position), the gross pathology (**p = 0.0001 for Ulcerative pathology), the TNM stage (**p = 0.003 for stage II and *p = 0.013 for stage III), the tumor size (*p = 0.014 for ≥ 10 mm3, ≤ 20 mm3, **p = 0.0001 for >20 mm3), the infiltration depth (*p = 0.034 for muscularis and **p = 0.001 for fibrosa), and the cell differentiation (*p = 0.011 for moderately differentiated tumors and *p = 0.021 for well differentiated tumors) as well.