MMP16 and schizophrenia: The possibility that genetic vulnerability may contribute to altered expression of matrix metalloproteases in schizophrenia is supported by converging results from several recent genetic association and genome-wide association studies showing that gene variants encoding for a number of these enzymes, including ADAMTSL3, ADAMTS12, ADAMTS16, ADAM22, and MMP-16, may be associated with this disorder [94–98].