Figure 4(a) indicated that the Ad-KLF-4 infection with a multiplicity of infection (MOI) of 1 or 5 dramatically promoted the KLF-4 mRNA level, at 12-hour postinfection (HPI) (p < 0.001 or p < 0.0001). And the promotion was significant since 3-hour postinfection and peaked at 12-hour postinfection (p < 0.0001, Figure 4(b)). And the KLF-4 promotion was also confirmed in protein level (p < 0.01, p < 0.001, or p < 0.0001; Figures 4(c) and 4(d)). Here, KLF4 is linked to infection.