Because histone acetyltransferases and histone deacetylases regulate histone acetylation, in order to investigate the causes of reduced H3 acetylation patterns in LADA patients, we assessed mRNA levels of histone acetyltransferases and histone deacetylases genes in CD4+ T lymphocytes by real-time quantitative PCR. Here, CD4 is linked to latent autoimmune diabetes in adults.