We further confirmed the elevation of BCL2 protein levels in nonalcoholic steatohepatitis (NASH), alcohol and HCV cirrhosis by Western blot (Fig. 6D).These results demonstrated a positive correlation of activation of BCL2 and H19 with the development of liver fibrosis and cirrhosis in both humans and mice. Here, H19 is linked to metabolic dysfunction-associated steatohepatitis.