To explore whether myocardial resistance to adiponectin is responsible for the positive association between myocardial redox state and adiponectin levels (systemic and EpAT expression), we studied the expression of ADIPOQ and adiponectin receptors (ADIPOR1, ADIPOR2, and CDH13) in the myocardium of patients with advanced coronary atherosclerosis. This evidence concerns the gene ADIPOR1 and coronary atherosclerosis.