TNF and Schnyder corneal dystrophy: Consistent with the original report by Nakamura et al. 24 we see a modest reduction in adipose tissue inflammation, albeit we did not observe reductions in macrophage infiltration or the expression of classical pro-inflammatory cytokines such as Tnfa and Il1b. In addition, both in the present study and that by Nakamura et al. 24 PKR KO mice fed a SCD were indistinguishable from their WT counterparts.