This resulted in 97 significantly (FDR < 0.05) overrepresented pathways, including multiple pathways related to TGF-β-, AhR- and NOTCH-signaling, blood coagulation, cell-cell and cell-matrix interactions, as well as pathways related to various diseases such as cancer and heart disease (Supplementary Table S6). The gene discussed is AHR; the disease is heart disorder.