MiR-103 increased CXCL1-dependent monocyte adhesion and rescued the decreased chemokine expression caused by knockdown of Dicer in ECs, indicating that reduced endothelial miR-103 levels limit monocyte adhesion and atherosclerosis in EC-Dicerflox mice by downregulating CXCL1. Here, CXCL1 is linked to atherosclerosis.