DUOX2 and asthma: Although DUOX2 was expressed in a much lower percentage of epithelium, a significant increase was seen in patients with nonneutrophilic asthma (0.97% ± 0.29%; P = .026) but not neutrophilic asthma (0.58% ± 0.15%; P = .072) compared with healthy control subjects (0.27% ± 0.07%), and expression was not differentially expressed in neutrophilic vs nonneutrophilic phenotypes (P = .258) (ANOVA, P = .045) (e-Fig 1).