In the recent years a number of genetic markers including certain genetic polymorphisms, specific genes, human lymphocyte antigen types, calcium dependent NFAT signaling, caspase-3, and TGF beta genes have been associated with coronary artery involvement in Kawasaki disease [45,46,47,48,49,50,51,52,53,54,55,56,57]. The gene discussed is CASP3; the disease is Kawasaki disease.