MSH2 and hereditary nonpolyposis colon cancer: “...hMSH2 maps to human chromosome 2p22-21 near a locus implicated inhereditary nonpolyposis coloncancer (HNPCC)...These data and reports indicating that S.cerevisiae msh2 mutations cause an instability ofdinucleotide repeats like those associated with HNPCC suggest thathMSH2 is theHNPCC gene...”