DISC-1 (Disrupted in Schizophrenia 1) protein, a molecule that determines susceptibility to schizophrenia, is crucial during embryogenesis due to its stimulatory actions on the non-canonical Wnt signaling pathway and its inhibition of glycogen synthase kinase 3-β (GSK-3β) (De Rienzo et al., 2011; Lipina et al., 2011). This evidence concerns the gene DISC1 and schizophrenia.